Neil McDonald's men won convincingly at the City Ground earlier on in the season as the Wanderers ran out 3-1 winners thanks to a double from Ricardo Vaz-Te and an effort from James Sinclair.
Unfortunately results for the second string have been patchy in recent weeks with just one win since the turn of the year coming just over two weeks ago away at Leeds United.
Forest are also in a similar run of form to that of Bolton and will be looking to put a recent defeat to Wolverhampton Wanderers behind them as they travel to Lancashire.
BOLTON RESERVES: Andy Oakes, Rhys Powell, Jason Talbot, Dale Whitehead, Bradley Hill, Jaroslaw Fojut, James Sinclair, Robert Sissons, Bedi Buval, Danny Stott, Karl Luisi
SUBS: Michael Gillan, Chris Howarth, Jamie Gibb, Craig Knowles, Luke Magill
FOREST RESERVES: Barry Roche, James Biggins, Martin Vickerton, Fernandez, Justyn Roberts, Kevin James, James Beaumont, Ross Gardner, Danny Blair, Jonathan Wilmet, Sam Mullarkey
SUBS: Craig Westcarr, Paddy Gamble, Matthew Glass, Robert Hughes, Felix Bastians